Unlocking the Power of the Ocean: PEPDOO®’s Precision Peptide Technology Leads a New Era in Marine Biomedicine
On June 8, World Oceans Day, PEPDOO® officially signed a technology transfer agreement for its Marine Bioactive Antihypertensive Peptide Preparation Process at a special event hosted by the Fujian Provincial Ocean and Fisheries Bureau. Centered around the theme “Deep Blue Technologies for Human Health,” this event marked a major milestone in China’s marine biomedical innovation.
Leveraging its proprietary OKPEP® Precision Peptide Technology, PEPDOO® transforms underutilized marine resources into bioactive “blue codes” that promote cardiovascular health — driving both scientific progress and sustainable ocean development.
Why Hypertension Needs a Natural Solution — And How Marine Peptides Deliver
Hypertension affects more than 245 million adults in China alone, with a prevalence rate of 27.9% among those over 18, according to the National Center for Cardiovascular Diseases (2019). Left uncontrolled, it significantly increases the risk of heart attack, stroke, and vascular disease.
Conventional blood pressure medications often have side effects and poor patient compliance. In contrast, bioactive antihypertensive peptides — especially those derived from marine proteins — offer a natural, side-effect-free alternative. These peptides work by inhibiting angiotensin-converting enzyme (ACE), a key mechanism for regulating blood pressure. Fish proteins are an abundant, renewable source of such peptides, paving the way for safe and sustainable therapeutics.

PEPDOO® OKPEP® Platform: Breakthrough in Precision Peptide Engineering
PEPDOO®’s scientific advantage lies in its proprietary OKPEP® platform, which integrates:
- AI-driven peptide modeling
- Biotarget-guided screening
- Directed enzymatic hydrolysis
- Patented membrane separation (ceramic + nanofiltration)
The result is a cutting-edge, cost-efficient production method for high-purity marine antihypertensive peptides. Compared to conventional resin chromatography, PEPDOO®’s method delivers:
- >90% peptide purity
- 82.7% ACE inhibitory activity
- 3x higher production efficiency
This innovation overcomes the scalability and purity limitations of traditional methods, making PEPDOO® a global leader in functional marine peptides.
Project Highlights: Marine Bioactive Antihypertensive Peptide Process
- ✅ Sustainable Sourcing
Utilizes renewable marine biomass instead of chemical synthesis, aligned with global health and green trends. - ✅ Innovative Manufacturing
Employs precision bioprocessing — including AI design, enzymatic hydrolysis, and membrane separation — to ensure stable, bioactive peptide production. - ✅ Broad Application Potential
Ideal for functional foods, medical nutrition (FSMP), and pharmaceuticals, offering natural solutions for managing hypertension.
Scientific Strength + Industrial Scale: PEPDOO® Sets the Benchmark
As a National High-Tech Enterprise, PEPDOO® has built a robust peptide innovation ecosystem:
- Holds over 150+ patents in precision peptide technology
- Recognized for “Advanced Marine Oligopeptide Engineering” by Chinese authorities
- Recycles fish by-products (scales, skins) into high-value peptide ingredients
- Named a “Sustainable Ocean Resource Development Model” by the Ministry of Natural Resources
PEPDOO® also operates a 40,000 m² smart manufacturing base, certified by CNAS, with full automation from hydrolysis to drying — enabling 6,000+ tons of annual output and global supply capabilities.

Industry Impact: From R&D to Global Commercialization
PEPDOO® bridges research and industry by:
- Partnering with leading institutions like Xiamen University and The Third Institute of Oceanography
- Establishing a Joint R&D Center for Marine Biofermentation Products
- Leading the formulation of 10+ industry standards, including “Marine Animal Peptides”
- Exporting peptide-based products to five continents, serving 5,000+ global partners
This latest antihypertensive peptide project exemplifies how PEPDOO®’s precision peptide technology transforms cutting-edge research into industrial-scale health solutions.
A New Era for Marine Biomedicine, Powered by Blue Innovation
As China’s marine economy exceeds 10 trillion RMB, PEPDOO® is pioneering the next generation of marine biopharmaceuticals through “blue technology.” By unlocking the functional potential of marine peptides, PEPDOO® delivers health innovations aligned with global goals such as Healthy China 2030 and carbon neutrality (“Dual Carbon”).
“The extreme metabolic systems of deep-sea life are a treasure trove for human health,” said a PEPDOO® executive at the signing ceremony. “With over 15 years of peptide expertise, we are leading the shift from traditional to precision peptide development.”
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