Mulberry Leaf Peptide – Patented Whitening Ingredient from a Source Manufacturer

A patented herbal peptide ingredient for beauty-from-within and functional nutrition.
Manufactured and supplied directly by PEPDOO® — your global source for clinically supported B2B peptide solutions.

Patented Mulberry Leaf Peptide: Proven Skin Brightening & Oral Bioavailability

Our Proprietary Dual-Enzyme Hydrolysis Patent Technology

PEPDOO® holds the exclusive Chinese patent (CN 115970182 A) for a proprietary dual-enzyme hydrolysis extraction method, enabling the efficient production of mulberry leaf peptides with molecular weight under 1000 Da.

This advanced process achieves a remarkable 76.7% inhibition of tyrosinase activity at just 2% peptide concentration, significantly outperforming traditional mulberry polyphenols and flavonoids in skin-brightening efficacy.

By combining amide enzyme pre-treatment with neutral and acidic protease hydrolysis, our method ensures high yield, superior bioavailability, and consistent peptide quality.

Step 1: Mulberry Leaf + Amide Enzyme Pre-treatment
Mulberry Leaf raw material undergoes amide enzyme pre-treatment to prepare proteins for hydrolysis.
Step 2: PC10F Neutral Protease Hydrolysis
PC10F Neutral Protease hydrolysis breaks down proteins into smaller peptides.
Step 3: 3.350 Acidic Protease Hydrolysis
3.350 Acidic Protease further hydrolyzes peptides to achieve desired molecular weight distribution.
Step 4: 1000Da Ultrafiltration
1000 Da ultrafiltration separates low molecular weight peptides for enhanced bioavailability.
Step 5: Spray Drying to Powder
Spray drying converts the purified peptide solution into stable powder form, ensuring long shelf-life and ease of application.

B2B Formulation Possibilities with Mulberry Leaf Peptide

PEPDOO® Mulberry Leaf Peptide offers patented, clinically backed solutions for diverse beauty-from-within and functional nutrition formulations. Explore versatile applications tailored for whitening, skin brightening, and synergistic blends with other proven actives.

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Nutricosmetics

Whitening capsules, beauty gummies, and oral supplements designed to promote radiant, youthful skin from within.

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Functional Beverages

Skin brightening RTDs and other functional drinks with superior bioavailability and pleasant taste.

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Topical Skincare

Anti-spot creams, serums, and lotions that inhibit melanin synthesis to improve skin clarity and brightness.

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Combination Formulations

Synergistic blends with glutathione, collagen peptides, vitamin C, and other whitening actives for enhanced efficacy.

As a patented mulberry leaf peptide ingredient with clinically proven skin brightening effects, PEPDOO® supports global B2B partners with innovative beauty-from-within and functional nutrition formulations.

Why Choose PEPDOO® as Your Trusted Peptide Supplier

At PEPDOO®, we combine science-backed innovation with end-to-end manufacturing capabilities to deliver high-performance functional peptides to global B2B partners. From mulberry leaf peptides to full-spectrum bioactives, we support your product from source to solution.

  • 🔬 Source Manufacturer with Full Traceability – Direct peptide production with transparent raw material sourcing.
  • 🧪 Exclusive Patent on Mulberry Peptide Extraction – Advanced enzymatic hydrolysis and fermentation technology.
  • 🏭 GMP Production + Global B2B Supply Chain – Scalable output with international logistics readiness.
  • 📄 Full Technical Documentation & Regulatory Support – COA, MSDS, stability data, and compliance files.
  • 🤝 OEM/ODM Customization Support – Tailored peptide solutions for supplements, skincare, and beverages.

Your Trusted Source Manufacturer for Mulberry Leaf Peptide

With a dedicated line for botanical peptide production, PEPDOO® delivers over 6,000 MT of peptide ingredients annually. Our patented Mulberry Leaf Peptide is entirely manufactured in-house—from raw mulberry leaf extraction and enzymatic hydrolysis to probiotic fermentation, membrane filtration, and precision-controlled spray drying. No outsourcing means full traceability and consistent quality—trusted by global brands in functional nutrition, digestive health, and metabolic wellness.

PEPDOO® Factory Exterior
Scientist working inside the fermentation workshop, monitoring production processes in a clean facility.
Two staff members recording data and operating fermentation equipment in a sterile workshop environment.
Scientist working with laboratory equipment in the EYOSON research facility.

3-stage In-house QC

Every batch verified through enzymatic, microbial & functional tests

Exported to 35+ Countries

Trusted by brands in EU, US, and Asia-Pacific

0 Recalls Since 2015

Proven safety & traceability

6,000 MT Capacity

Fully vertical peptide manufacturing process

Your Trusted Global Partner in Peptide Innovation

PEPDOO® delivers a full spectrum of animal- and plant-derived peptides with a focus on patented innovation, bioactive purity, and B2B manufacturing excellence. As the original manufacturer of Mulberry Leaf Peptide, we utilize exclusive extraction, enzymatic hydrolysis, and Lactobacillus fermentation technologies to create clinically supported, scalable ingredients. Our botanical peptide solutions are trusted by global brands in digestive health, blood sugar support, and metabolic wellness.


Patent No. ZL201820444344.5
Thermostatically Controlled Enzymatic Hydrolysis Tank
中文名称:一种恒温控制的酶解罐
This patented system ensures precise temperature control and efficient enzymatic breakdown during the production of high-purity ginseng peptides.

Patent No. ZL202220562037.3
Integrated Concentration Device
中文名称:一种集成浓缩装置
This patented system improves production efficiency by concentrating peptides with minimal nutrient loss, preserving their functional activity.

Patent No. ZL202221480883.7
Nano Peptide Separation and Purification Device
中文名称:一种纳米肽分离纯化装置
This patented nanofiltration technology enables the separation of bioactive peptides with enhanced purity, solubility, and bioavailability.

Let’s Create Something Powerful Together

Ready to formulate your next liver-support innovation? PEPDOO® offers private label, custom peptide blends, and R&D partnership options tailored for your target market.

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